Program keeps closing down unexpectedly and won't recognize mouse on some areas

I've got the trial of painter essentials 7. It started out working great, but about a week in and it will shut down randomly. I close down everything, so that this is the only program running. 

Today I've come across another issue. The windows that hold layers doesn't seem to recognize the mouse. I can't use my mouse or a stylus to move layers, or move the window. Its like I'm not even clicking on them. 

I'm running the latest edition of windows.